Sodium Iodide → Iodopropyldimethylvinylsilane

HRID 1170069

반응식

HRID 1170069 반응식
Cl[CH2:2][CH2:3][CH2:4][SiH2:5][CH:6]=[C:7]([CH3:9])[CH3:8].[I-:10].[Na+]>CC(CC)=O>[I:10][CH2:2][CH2:3][CH2:4][SiH2:5][CH:6]=[C:7]([CH3:9])[CH3:8]

참가 물질

4

반응물 2

HCID 5238Sodium IodideHCID 131715857Chloropropyldimethylvinylsilane

생성물 1

HCID 131728415Iodopropyldimethylvinylsilane수율 53.6%

시약·촉매·용매 1

HCID 6569Methyl Ethyl Ketone용매

반응 조건

온도
75 °C

실험 절차

To a stirring solution of chloropropyldimethylvinylsilane (645 g) in ethyl methyl ketone (4.65 L), sodium iodide (1.215 Kg) was added under nitrogen and the mixture heated at 75° C. for 24 hr. The reaction mixture was cooled and added D.M. Water (1.62 L) and separated organic layer. The aqueous layer was re-extracted with ethyl methyl ketone (1.16 L) and the extract combined with the organic layer. The organic layer was dried on sodium sulfate and evaporated to dryness. Orange oil was purified by vacuum distillation to give colourless liquid the title product (540 g).

후처리

  1. temperatureThe reaction mixture was cooled
  2. additionadded D.M
  3. customWater (1.62 L) and separated organic layer
  4. extractionThe aqueous layer was re-extracted with ethyl methyl ketone (1.16 L)
  5. customThe organic layer was dried on sodium sulfate
  6. customevaporated to dryness
  7. distillationOrange oil was purified by vacuum distillation

출처 및 근거

ORD 기록
ord-8205c8f0b2644da4b9373ef46ef7c4f7
출처 데이터셋
uspto-grants-2010_11
특허 번호
US07825257B1

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