2-Chloro-5-nitroquinoline → N5-(2-Methoxy-pyridin-3-ylmethyl)-N2-(5-methyl-furan-2-ylmethyl)-quinoline-2,5-diamine

HRID 1170095

반응식

HRID 1170095 반응식
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][C:8](Cl)=[N:9]2)([O-])=O.[CH3:15][C:16]1[O:20][C:19]([CH2:21][NH2:22])=[CH:18][CH:17]=1.[CH3:23][O:24][C:25]1[C:30]([CH:31]=O)=[CH:29][CH:28]=[CH:27][N:26]=1>>[CH3:23][O:24][C:25]1[C:30]([CH2:31][NH:1][C:4]2[C:5]3[CH:6]=[CH:7][C:8]([NH:22][CH2:21][C:19]4[O:20][C:16]([CH3:15])=[CH:17][CH:18]=4)=[N:9][C:10]=3[CH:11]=[CH:12][CH:13]=2)=[CH:29][CH:28]=[CH:27][N:26]=1

참가 물질

4

반응물 3

HCID 3192512-Chloro-5-nitroquinolineHCID 27246835-Methyl-2-furylmethylamineHCID 125333912-Methoxypyridine-3-carbaldehyde

생성물 1

HCID 24987489N5-(2-Methoxy-pyridin-3-ylmethyl)-N2-(5-methyl-furan-2-ylmethyl)-quinoline-2,5-diamine

실험 절차

The title compound, MS: m/e=375.1 (M+H+), was prepared from 5-nitro-2-chloroquinoline, 5-methyl-2-furanmethanamine and 2-methoxy-3-pyridinecarboxaldehyde as described in example 26.

출처 및 근거

ORD 기록
ord-cf601ed15e0847a5ade7be34e3473545
출처 데이터셋
uspto-grants-2010_11
특허 번호
US07825253B2

연결된 노트

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