2-Chloro-5-nitroquinoline → 3-({2-[(5-Methyl-furan-2-ylmethyl)-amino]-quinolin-5-ylamino}-methyl)-benzenesulfonamide
반응식
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][C:8](Cl)=[N:9]2)([O-])=O.[CH3:15][C:16]1[O:20][C:19]([CH2:21][NH2:22])=[CH:18][CH:17]=1.[CH:23]([C:25]1[CH:26]=[C:27]([S:31]([NH2:34])(=[O:33])=[O:32])[CH:28]=[CH:29][CH:30]=1)=O>>[CH3:15][C:16]1[O:20][C:19]([CH2:21][NH:22][C:8]2[CH:7]=[CH:6][C:5]3[C:10](=[CH:11][CH:12]=[CH:13][C:4]=3[NH:1][CH2:23][C:25]3[CH:26]=[C:27]([S:31]([NH2:34])(=[O:33])=[O:32])[CH:28]=[CH:29][CH:30]=3)[N:9]=2)=[CH:18][CH:17]=1참가 물질
4
실험 절차
The title compound, MS: m/e=423.1 (M+H+), was prepared from 5-nitro-2-chloroquinoline, 5-methyl-2-furanmethanamine and 3-formylbenzenesulfonamide (CAS 1778-37-6) as described in example 26.
출처 및 근거
- ORD 기록
- ord-9442637a6e834b4fa707cf1f34b0dfc2