4-Fluorobenzenesulfonyl chloride → 4-Fluoro-N-[2-(2-trifluoromethoxy-benzylamino)-quinolin-5-yl]-benzenesulfonamide
반응식
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][C:8](Cl)=[N:9]2)([O-])=O.[F:15][C:16]1[CH:21]=[CH:20][C:19]([S:22](Cl)(=[O:24])=[O:23])=[CH:18][CH:17]=1.[F:26][C:27]([F:38])([F:37])[O:28][C:29]1[CH:36]=[CH:35][CH:34]=[CH:33][C:30]=1[CH2:31][NH2:32]>>[F:15][C:16]1[CH:21]=[CH:20][C:19]([S:22]([NH:1][C:4]2[CH:13]=[CH:12][CH:11]=[C:10]3[C:5]=2[CH:6]=[CH:7][C:8]([NH:32][CH2:31][C:30]2[CH:33]=[CH:34][CH:35]=[CH:36][C:29]=2[O:28][C:27]([F:26])([F:37])[F:38])=[N:9]3)(=[O:24])=[O:23])=[CH:18][CH:17]=1참가 물질
4
실험 절차
The title compound, MS: m/e=491.8 (M+H+), was prepared in accordance with the general method of example 89 from 5-nitro-2-chloroquinoline, 4-fluorobenzenesulfonylchloride and 2-(trifluoromethoxy)benzylamine.
출처 및 근거
- ORD 기록
- ord-5a8efe085d85435d924e40e836d8b032