(1H-indol-4-yl)methanamine → N5-(1H-Indol-4-ylmethyl)-N2-(2-methyl-benzofuran-7-yl)-quinoline-2,5-diamine

HRID 1170164

반응식

HRID 1170164 반응식
I[C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][C:6](Cl)=[N:7]2.[CH3:13][C:14]1[O:15][C:16]2[C:22]([NH2:23])=[CH:21][CH:20]=[CH:19][C:17]=2[CH:18]=1.[NH2:24][CH2:25][C:26]1[CH:34]=[CH:33][CH:32]=[C:31]2[C:27]=1[CH:28]=[CH:29][NH:30]2>>[NH:30]1[C:31]2[C:27](=[C:26]([CH2:25][NH:24][C:2]3[C:3]4[CH:4]=[CH:5][C:6]([NH:23][C:22]5[C:16]6[O:15][C:14]([CH3:13])=[CH:18][C:17]=6[CH:19]=[CH:20][CH:21]=5)=[N:7][C:8]=4[CH:9]=[CH:10][CH:11]=3)[CH:34]=[CH:33][CH:32]=2)[CH:28]=[CH:29]1

참가 물질

4

반응물 3

HCID 280302(1H-indol-4-yl)methanamineHCID 31574852-Methyl-benzofuran-7-ylamineHCID 457894242-Chloro-5-iodoquinoline

생성물 1

HCID 24990107N5-(1H-Indol-4-ylmethyl)-N2-(2-methyl-benzofuran-7-yl)-quinoline-2,5-diamine

실험 절차

The title compound, MS: m/e=419.1 (M+H+), was prepared in accordance with the general method of example 1 from 5-iodo-2-chloroquinoline, (2-methyl-1-benzofuran-7-yl)amine and 4-aminomethylindole.

출처 및 근거

ORD 기록
ord-407cd403e32744038291d149148e0964
출처 데이터셋
uspto-grants-2010_11
특허 번호
US07825253B2

연결된 노트

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