2,2,2-Trifluoroethylhydrazine → Pde10-IN-5

HRID 1170267노트

반응식

HRID 1170267 반응식
C[N:2]1[CH:6]=[C:5]([C:7]2[CH:12]=[CH:11][N:10]=[CH:9][CH:8]=2)[C:4]([C:13]2[CH:30]=[CH:29][C:16]([O:17][CH2:18][C:19]3[CH:28]=[CH:27][C:26]4[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=4)[N:20]=3)=[CH:15][CH:14]=2)=[N:3]1.[F:31][C:32]([F:37])([F:36])[CH2:33]NN>>[N:10]1[CH:9]=[CH:8][C:7]([C:5]2[CH:6]=[N:2][N:3]([CH2:33][C:32]([F:37])([F:36])[F:31])[C:4]=2[C:13]2[CH:30]=[CH:29][C:16]([O:17][CH2:18][C:19]3[CH:28]=[CH:27][C:26]4[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=4)[N:20]=3)=[CH:15][CH:14]=2)=[CH:12][CH:11]=1

참가 물질

3

반응물 2

HCID 787402,2,2-TrifluoroethylhydrazineHCID 115819362-((4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy)methyl)quinoline

생성물 1

HCID 11554381Pde10-IN-5

실험 절차

Following the procedure for the preparation of 2-[4-(1-Methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)-phenoxymethyl]-quinoline but substituting (2,2,2-trifluoro-ethyl)-hydrazine provided the title compound. MS: (M+H m/z=461.2).

출처 및 근거

ORD 기록
ord-bedb31bde42449b8896e06a5e1219983
출처 데이터셋
uspto-grants-2010_11
특허 번호
US07825254B2

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