2-(Pyridin-4-yl)-1-(4-(quinolin-2-ylmethoxy)phenyl)ethan-1-one → 1-(4-Benzyloxy-2-fluoro-phenyl)-2-pyridin-4-yl-ethanone
반응식
[N:1]1[CH:6]=[CH:5][C:4]([CH2:7][C:8]([C:10]2[CH:15]=[CH:14][C:13]([O:16][CH2:17][C:18]3[CH:27]=[CH:26][C:25]4[C:20](=[CH:21]C=CC=4)N=3)=[CH:12][CH:11]=2)=[O:9])=[CH:3][CH:2]=1.C(OC1C=CC(C(N(OC)C)=O)=C([F:48])C=1)C1C=CC=CC=1>>[CH2:17]([O:16][C:13]1[CH:12]=[CH:11][C:10]([C:8](=[O:9])[CH2:7][C:4]2[CH:3]=[CH:2][N:1]=[CH:6][CH:5]=2)=[C:15]([F:48])[CH:14]=1)[C:18]1[CH:27]=[CH:26][CH:25]=[CH:20][CH:21]=1참가 물질
3
실험 절차
Following the procedure for the preparation of 2-pyridin-4-yl-1-[4-(quinolin-2-ylmethoxy)-phenyl]-ethanone but substituting 4-Benzyloxy-2-fluoro-N-methoxy-N-methyl-benzamide provided the title compound. MS: (M+H m/z=322.1).
출처 및 근거
- ORD 기록
- ord-376a492e685144d6b94a3ffc51d989cb
- 출처 데이터셋
- uspto-grants-2010_11