4-[3-(4-Benzyloxy-2-fluoro-phenyl)-1-methyl-1H-pyrazol-4-yl]-pyridine → 3-Fluoro-4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)-phenol
반응식
CN1C=C(C2C=CN=CC=2)C(C2C=CC(O)=CC=2)=N1.C([O:27][C:28]1[CH:33]=[CH:32][C:31]([C:34]2[C:38]([C:39]3[CH:44]=[CH:43][N:42]=[CH:41][CH:40]=3)=[CH:37][N:36]([CH3:45])[N:35]=2)=[C:30]([F:46])[CH:29]=1)C1C=CC=CC=1>>[F:46][C:30]1[CH:29]=[C:28]([OH:27])[CH:33]=[CH:32][C:31]=1[C:34]1[C:38]([C:39]2[CH:40]=[CH:41][N:42]=[CH:43][CH:44]=2)=[CH:37][N:36]([CH3:45])[N:35]=1참가 물질
3
실험 절차
Following the procedure for the preparation of 4-(1-Methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)-phenol but substituting 4-[3-(4-Benzyloxy-2-fluoro-phenyl)-1-methyl-1H-pyrazol-4-yl]-pyridine provided the title compound. MS: (M+H m/z=270.1).
출처 및 근거
- ORD 기록
- ord-cc201952e0584e5c9e5adc870e7e5a8e
- 출처 데이터셋
- uspto-grants-2010_11