2-Naphthyl isopropyl ketone → alpha-Bromoisopropyl 2-naphthyl ketone

HRID 1170824노트

반응식

HRID 1170824 반응식
[Br-:1].[Br-].[Br-].C1([N+](C)(C)C)C=CC=CC=1.C1([N+](C)(C)C)C=CC=CC=1.C1([N+](C)(C)C)C=CC=CC=1.[CH:34]([C:37]([C:39]1[CH:48]=[CH:47][C:46]2[C:41](=[CH:42][CH:43]=[CH:44][CH:45]=2)[CH:40]=1)=[O:38])([CH3:36])[CH3:35]>O1CCCC1>[CH:40]1[C:41]2[C:46](=[CH:45][CH:44]=[CH:43][CH:42]=2)[CH:47]=[CH:48][C:39]=1[C:37]([C:34]([Br:1])([CH3:36])[CH3:35])=[O:38]

참가 물질

4

반응물 2

HCID 109654952-Naphthyl isopropyl ketoneHCID 17977687Phenyltrimethylammonium bromide dibromide

생성물 1

HCID 12587407alpha-Bromoisopropyl 2-naphthyl ketone수율 172.2%

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

2.16 g of phenyltrimethylammonium tribromide was added to a mixture comprising 1.14 g of 2-naphthyl isopropyl ketone and 25 ml of tetrahydrofuran, and the mixture was reacted at room temperature for 3 hours. The reaction mixture was filtered, and the filtrate was concentrated under reduced pressure to obtain 1.59 g of oily α-bromoisopropyl 2-naphthyl ketone.

후처리

  1. customthe mixture was reacted at room temperature for 3 hours
  2. filtrationThe reaction mixture was filtered
  3. concentrationthe filtrate was concentrated under reduced pressure

출처 및 근거

ORD 기록
ord-5c95fc9c44a248b9a583e9ef409944ea
출처 데이터셋
uspto-grants-2010_11
특허 번호
US07829501B2

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