Methyl 2-[(4-nitronaphthalen-1-yl)oxy]acetate → Methyl 2-((4-aminonaphthalen-1-yl)oxy)acetate
반응식
[CH3:1][O:2][C:3](=[O:19])[CH2:4][O:5][C:6]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:9]([N+:16]([O-])=O)=[CH:8][CH:7]=1.[H][H]>CO.[Pd]>[CH3:1][O:2][C:3](=[O:19])[CH2:4][O:5][C:6]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:9]([NH2:16])=[CH:8][CH:7]=1참가 물질
5
실험 절차
(4-Nitro-naphthalen-1-yloxy)-acetic acid methyl ester (0.90 g) and 10% Pd/C (90 mg) in MeOH (150 ml) is stirred at room temperature under 1 atmosphere of hydrogen for 4 h. The mixture is then filtered through Celite® and evaporated to dryness to provide (4-amino-naphthalen-1-yloxy)-acetic acid methyl ester (0.72 g). MS 232 (M+1).
후처리
- filtrationThe mixture is then filtered through Celite®
- customevaporated to dryness
출처 및 근거
- ORD 기록
- ord-83aea31b3e8147c49dbede96beb4da31
- 출처 데이터셋
- uspto-grants-2010_11
- 특허 번호
- US07829560B2
반응 노트
불러오는 중…