Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diisobutylaluminum hydride → (2-(Benzyloxy)-4-iodophenyl)methanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diisobutylaluminum hydride | HCID 14487 | — |
| 반응물 | Methyl 2-(benzyloxy)-4-iodobenzoate | HCID 66990993 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | (2-(Benzyloxy)-4-iodophenyl)methanol | HCID 68417547 | — |
반응 단계
The procedure is the same as that described above, using 14 g of methyl 2-benzyloxy-4-iodobenzoate, 350 ml of toluene and 72 ml of DiBAlH. The product is purified by chromatography on a silica column, eluted with a heptane/ethyl acetate 9:1 mixture. After evaporation of the solvents, 12.2 g (99%) of the expected compound are recovered in the form of a yellow oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07829588B2 |
| 출처 데이터셋 | uspto-grants-2010_11 |
| ORD ID | ord-6be7912f618e4550a1e5a34776ba1fef |
| 출처 메모 | uspto-grants-2010_11 |