Hexane → HCID 57562627, 화합물

HRID 1172427노트

반응식

HRID 1172427 반응식
[NH2:1][C:2]1[N:7]=[C:6]([C:8]([O:10][CH3:11])=[O:9])[CH:5]=[C:4]([Br:12])[CH:3]=1.[C:13]([N:21]=[C:22]=[S:23])(=[O:20])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1.CCCCCC>O1CCCC1>[C:13]([NH:21][C:22](=[S:23])[NH:1][C:2]1[N:7]=[C:6]([C:8]([O:10][CH3:11])=[O:9])[CH:5]=[C:4]([Br:12])[CH:3]=1)(=[O:20])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

참가 물질

5

반응물 3

HCID 8058HexaneHCID 68284Benzoyl isothiocyanateHCID 29919299Methyl 6-amino-4-bromopyridine-2-carboxylate

생성물 1

HCID 57562627HCID 57562627, 화합물

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

2.74 g of methyl 6-amino-4-bromopyridine-2-carboxylate was dissolved in 15 ml of tetrahydrofuran and 1.63 ml of benzoyl isothiocyanate was added thereto, followed by stirring at room temperature for 13 hours. To the reaction mixture was added 40 ml of hexane. The resulting solid was filtered and washed with hexane. The obtained solid was dried in vacuo to give the title compound.

후처리

  1. filtrationThe resulting solid was filtered
  2. washwashed with hexane
  3. customThe obtained solid was dried in vacuo

출처 및 근거

ORD 기록
ord-3ed8026681ef4d92b94a658b2e7ad497
출처 데이터셋
uspto-grants-2010_11
특허 번호
US07834018B2

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