9-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-4-fluoro-benzylamide → 9-{4-[4-(8-chloro-quinolin-2-yl)-piperazin-1-yl]-butyl}-9H-fluorene-9-carboxylic Acid-4-fluoro-benzylamide

반응식

[Cl:30][c:31]1[cH:32][cH:33][cH:34][c:35]2[cH:36][cH:37][c:38]([N:41]3[CH2:42][CH2:43][NH:44][CH2:45][CH2:46]3)[n:39][c:40]12.[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][NH:7][C:8](=[O:9])[C:10]2([CH2:23][CH2:24][CH2:25][CH2:26][Br:27])[c:11]3[cH:12][cH:13][cH:14][cH:15][c:16]3-[c:17]3[cH:18][cH:19][cH:20][cH:21][c:22]32)[cH:28][cH:29]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][NH:7][C:8](=[O:9])[C:10]2([CH2:23][CH2:24][CH2:25][CH2:26][N:44]3[CH2:43][CH2:42][N:41]([c:38]4[cH:37][cH:36][c:35]5[cH:34][cH:33][cH:32][c:31]([Cl:30])[c:40]5[n:39]4)[CH2:46][CH2:45]3)[c:11]3[cH:12][cH:13][cH:14][cH:15][c:16]3-[c:17]3[cH:18][cH:19][cH:20][cH:21][c:22]32)[cH:28][cH:29]1

참가 물질

반응물 2

HCID 226362389-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-4-fluoro-benzylamide

HCID 226362878-Chloro-2-piperazin-1-yl-quinoline

생성물 1

HCID 226362479-{4-[4-(8-chloro-quinolin-2-yl)-piperazin-1-yl]-butyl}-9H-fluorene-9-carboxylic Acid-4-fluoro-benzylamide

출처 및 근거

ORD 기록: ord-f49203493ac247dc9f9d73742cf4255f
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

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