Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Methoxyphenol → 1-[4-(4-Chlorophenoxy)-2-propylphenyl]-2-(4-methoxyphenoxy)ethanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Methoxyphenol | HCID 9015 | — |
| 반응물 | Cesium carbonate | HCID 10796 | — |
| 반응물 | 2-Bromo-1-[4-(4-chlorophenoxy)-2-propylphenyl]ethanone | HCID 57420141 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | 1-[4-(4-Chlorophenoxy)-2-propylphenyl]-2-(4-methoxyphenoxy)ethanone | HCID 68692754 | — |
반응 단계
A mixture of the product from Step 8 (0.50 g, 1.4 mmol), p-methoxyphenol (2.8 mmol) and cesium carbonate (0.91 g, 2.8 mmol) in DMF (10 mL) was stirred at room temperature for 1 h. The reaction mixture was diluted with ethyl acetate and washed with water. The solvent was evaporated and the residue was purified by chromatography on silica gel to give the title product as an oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07834036B2 |
| 출처 데이터셋 | uspto-grants-2010_11 |
| ORD ID | ord-d0b2a8c484c34129829722107e95272c |
| 출처 메모 | uspto-grants-2010_11 |