Hydroxylamine → HCID 178458441, 화합물
반응식
[Cl:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[O:10][CH:11]([CH3:13])[CH3:12])[C:5]#[N:6].[NH2:14][OH:15]>C(O)C>[Cl:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[O:10][CH:11]([CH3:13])[CH3:12])[C:5]([NH:14][OH:15])=[NH:6]참가 물질
4
반응 조건
- 온도
- 60 °C
실험 절차
Into a round bottom flask was added 3-chloro-4-isopropoxy-benzonitrile (5.00 g, 25.6 mmol), hydroxylamine (50% by weight in water, 1.86 mL, 28.1 mmol) and ethanol (150 mL). The mixture was heated at about 60° C. overnight. Upon completion of the reaction, the mixture was concentrated to dryness under reduced pressure to give 3-chloro-N-hydroxy-4-isopropoxy-benzamidine (5.76 g, 94%) as a light yellow solid.
후처리
- customUpon completion of the reaction
- concentrationthe mixture was concentrated to dryness under reduced pressure
출처 및 근거
- ORD 기록
- ord-9ac6e34e096d415285a50f8a23ebdfab
- 출처 데이터셋
- uspto-grants-2010_11
- 특허 번호
- US07834039B2
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