4-Fluorophenol → 4-[{3-[(4-Fluorophenyl)oxy]propyl}(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile

HRID 1173401노트

반응식

HRID 1173401 반응식
[OH:1][CH2:2][CH2:3][CH2:4][N:5]([CH2:18][C:19]([F:22])([F:21])[F:20])[C:6]1[CH:13]=[CH:12][C:9]([C:10]#[N:11])=[C:8]([C:14]([F:17])([F:16])[F:15])[CH:7]=1.[F:23][C:24]1[CH:29]=[CH:28][C:27](O)=[CH:26][CH:25]=1>>[F:23][C:24]1[CH:29]=[CH:28][C:27]([O:1][CH2:2][CH2:3][CH2:4][N:5]([CH2:18][C:19]([F:20])([F:21])[F:22])[C:6]2[CH:13]=[CH:12][C:9]([C:10]#[N:11])=[C:8]([C:14]([F:16])([F:15])[F:17])[CH:7]=2)=[CH:26][CH:25]=1

참가 물질

3

반응물 2

HCID 97324-FluorophenolHCID 866062484-[(3-Hydroxypropyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile

생성물 1

HCID 115462624-[{3-[(4-Fluorophenyl)oxy]propyl}(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile

실험 절차

Synthesized as described in Example 1C from 4-[(3-hydroxypropyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile and 4-fluorophenol: MS (ES) m/z 421 (M+1)

후처리

  1. customSynthesized

출처 및 근거

ORD 기록
ord-4463397ff0fc407385a7f97e81a844eb
출처 데이터셋
uspto-grants-2010_11
특허 번호
US07834063B2

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