4-Methoxyphenol → 4-[(3-{[4-(Methyloxy)phenyl]oxy}propyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile

HRID 1173402노트

반응식

HRID 1173402 반응식
[OH:1][CH2:2][CH2:3][CH2:4][N:5]([CH2:18][C:19]([F:22])([F:21])[F:20])[C:6]1[CH:13]=[CH:12][C:9]([C:10]#[N:11])=[C:8]([C:14]([F:17])([F:16])[F:15])[CH:7]=1.[CH3:23][O:24][C:25]1[CH:30]=[CH:29][C:28](O)=[CH:27][CH:26]=1>>[CH3:23][O:24][C:25]1[CH:30]=[CH:29][C:28]([O:1][CH2:2][CH2:3][CH2:4][N:5]([CH2:18][C:19]([F:20])([F:21])[F:22])[C:6]2[CH:13]=[CH:12][C:9]([C:10]#[N:11])=[C:8]([C:14]([F:16])([F:15])[F:17])[CH:7]=2)=[CH:27][CH:26]=1

참가 물질

3

반응물 2

HCID 90154-MethoxyphenolHCID 866062484-[(3-Hydroxypropyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile

생성물 1

HCID 117189804-[(3-{[4-(Methyloxy)phenyl]oxy}propyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile

실험 절차

Synthesized as described in Example 1C from 4-[(3-hydroxypropyl)(2,2,2-trifluoroethyl)amino]-2-(trifluoromethyl)benzonitrile and 4-methoxyphenol: MS (ESI) m/z 433 (M+1).

후처리

  1. customSynthesized

출처 및 근거

ORD 기록
ord-9fbd2c34203340c4b7ce618233b15395
출처 데이터셋
uspto-grants-2010_11
특허 번호
US07834063B2

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