Aniline → N2-[4-Cyano-3-(trifluoromethyl)phenyl]-N2-(cyclopropylmethyl)-N1-phenylglycinamide

HRID 1173498노트

반응식

HRID 1173498 반응식
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([N:9]([CH2:14][CH:15]2[CH2:17][CH2:16]2)[CH2:10][C:11]([OH:13])=O)=[CH:5][C:4]=1[C:18]([F:21])([F:20])[F:19])#[N:2].[NH2:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>>[C:1]([C:3]1[CH:8]=[CH:7][C:6]([N:9]([CH2:14][CH:15]2[CH2:17][CH2:16]2)[CH2:10][C:11]([NH:22][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)=[O:13])=[CH:5][C:4]=1[C:18]([F:21])([F:20])[F:19])#[N:2]

참가 물질

3

반응물 2

HCID 6115AnilineHCID 11369986N-[4-Cyano-3-(trifluoromethyl)phenyl]-N-(cyclopropylmethyl)glycine

생성물 1

HCID 70831247N2-[4-Cyano-3-(trifluoromethyl)phenyl]-N2-(cyclopropylmethyl)-N1-phenylglycinamide

실험 절차

Synthesized as described for Example 91C using N-[4-cyano-3-(trifluoromethyl)phenyl]-N-(cyclopropylmethyl)glycine and aniline: MS (APCI) m/z 374 (M+1).

후처리

  1. customSynthesized

출처 및 근거

ORD 기록
ord-cc2a0f0d9e3c42bb810297ce5495f2b9
출처 데이터셋
uspto-grants-2010_11
특허 번호
US07834063B2

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