Ethanol → HCID 10909830, 화합물
반응식
Cl[C@H:2]([C@H:8]([OH:12])[CH2:9][CH2:10][CH3:11])[C:3]([O:5][CH2:6][CH3:7])=[O:4].C(O)C.C(=O)([O-])[O-].[K+].[K+]>C(OC)(C)(C)C>[CH2:9]([C@H:8]1[O:12][C@@H:2]1[C:3]([O:5][CH2:6][CH3:7])=[O:4])[CH2:10][CH3:11]참가 물질
5
반응 조건
- 온도
- 15 °C
실험 절차
Ethyl (2R,3R)-2-chloro-3-hydroxyhexanoate (1.0 g, 5 mmol), ethanol (10 ml) and potassium carbonate (2.1 g, 15 mmol) were mixed, and the mixture was stirred at 15° C. for 14 hours. Methyl tert-butyl ether (20 ml) was added. The mixture was washed with water (10 ml) three times. The organic layer was concentrated under reduced pressure to obtain the title compound (0.83 g, yield: 100%).
후처리
- washThe mixture was washed with water (10 ml) three times
- concentrationThe organic layer was concentrated under reduced pressure
출처 및 근거
- ORD 기록
- ord-a0e2ece933e3448495c9834afd1870b6
- 출처 데이터셋
- uspto-grants-2010_11
- 특허 번호
- US07834190B2
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