Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Phthalimidomethyl-6-(4-dipropylaminobutyl)naphthalene → 2-Aminomethyl-6-(4-dipropylaminobutyl)naphthalene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Phthalimidomethyl-6-(4-dipropylaminobutyl)naphthalene | HCID 21084392 | — |
| 용매 | Monomethylamine methanol | HCID 57454252 | — |
| 생성물 | 2-Aminomethyl-6-(4-dipropylaminobutyl)naphthalene | HCID 21084390 | 127.5% |
반응 단계
The compound (75.0 mg) obtained in Example 124-3 was dissolved in a 40% methylamine/methanol solution (2.0 ml) and stirred overnight at room temperature. After completion of the reaction, the solvent was distilled off and then the residue was added with a 1 mol/l sodium hydroxide aqueous solution and stirred. The solution was subjected to extraction with chloroform and the extract was then washed with saturated saline solution. Subsequently, the organic layer was dried with anhydrous sodium sulfate and the solvent was then distilled off, thereby obtaining the subject compound (67.5 mg) as a colorless oily substance.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07833991B2 |
| 출처 데이터셋 | uspto-grants-2010_11 |
| ORD ID | ord-9c7e9fee8f374433950539a7e56d776f |
| 출처 메모 | uspto-grants-2010_11 |