1-Butanaminium, N,N,N-tributyl-, azide → HCID 10057735, 화합물

HRID 1174395

반응식

HRID 1174395 반응식
FC(F)(F)S(O[C@@H:7]1[C:11]([CH3:13])([CH3:12])[CH2:10][O:9][C:8]1=[O:14])(=O)=O.[N-:17]=[N+:18]=[N-:19].C([N+](CCCC)(CCCC)CCCC)CCC>C1(C)C=CC=CC=1.CCOCC>[N:17]([C@H:7]1[C:11]([CH3:13])([CH3:12])[CH2:10][O:9][C:8]1=[O:14])=[N+:18]=[N-:19]

참가 물질

5

반응물 2

HCID 57432321-Butanaminium, N,N,N-tributyl-, azideHCID 10106752(R)-4,4-dimethyl-2-oxotetrahydrofuran-3-yl trifluoromethanesulfonate

생성물 1

HCID 10057735HCID 10057735, 화합물

시약·촉매·용매 2

HCID 1140Toluene용매HCID 3283Diethyl Ether용매

실험 절차

To a solution containing the product from Example 174A (4.6 g, 17.56 mmol) in toluene (80.0 mL) was added tetra-n-butylammonium azide (5.0 g, 17.57 mmol) at room temperature, and the mixture was stirred for 5 hours. The reaction was diluted with ether and washed with water, dilute NaHCO3, 10% citric acid and brine. The organic layer was dried over MgSO4, filtered and concentrated to give the crude product, which was used without further purification (2.79 g).

후처리

  1. washwashed with water, dilute NaHCO3, 10% citric acid and brine
  2. dry with materialThe organic layer was dried over MgSO4
  3. filtrationfiltered
  4. concentrationconcentrated

출처 및 근거

ORD 기록
ord-a5df6eee4331436b851fd7a0e0d03686
출처 데이터셋
uspto-grants-2010_11
특허 번호
US07834043B2

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