3-Phenoxybenzoic acid → n-{2-[(2-Dimethylamino-ethyl)-methyl-amino]-benzothiazol-6-yl}-3-phenoxy-benzamide

HRID 1174965

반응식

HRID 1174965 반응식
[O:1]([C:8]1[CH:9]=[C:10]([CH:14]=[CH:15][CH:16]=1)[C:11]([OH:13])=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:17][N:18]([CH3:33])[CH2:19][CH2:20][N:21]([CH3:32])[C:22]1[S:23][C:24]2[CH:30]=[C:29]([NH2:31])[CH:28]=[CH:27][C:25]=2[N:26]=1>>[CH3:17][N:18]([CH3:33])[CH2:19][CH2:20][N:21]([CH3:32])[C:22]1[S:23][C:24]2[CH:30]=[C:29]([NH:31][C:11](=[O:13])[C:10]3[CH:14]=[CH:15][CH:16]=[C:8]([O:1][C:2]4[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=4)[CH:9]=3)[CH:28]=[CH:27][C:25]=2[N:26]=1

참가 물질

3

반응물 2

HCID 195393-Phenoxybenzoic acidHCID 55226563N2-(2-Dimethylamino-ethyl)-N2-methyl-benzothiazole-2,6-diamine

생성물 1

HCID 57771758n-{2-[(2-Dimethylamino-ethyl)-methyl-amino]-benzothiazol-6-yl}-3-phenoxy-benzamide

실험 절차

The title compound is prepared by following General Method A, using 3-phenoxy-benzoic acid (0.22 g, 1.04 mmol), and N*2*-(2-dimethylamino-ethyl)-N*2*-methyl-benzothiazole-2,6-diamine (0.20 g, 0.80 mmol) to afford an off-white solid (0.19 g, 53%). LC/MS: Retention time=4.45 nm in; (m/z): calcd for C25H2(N4O2S (M+H)+: 447.6; found: 447.3.

출처 및 근거

ORD 기록
ord-8ec71a69e9324abe86eeb9dbc601afe3
출처 데이터셋
uspto-grants-2010_11
특허 번호
US07838543B2

연결된 노트

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