HCID 66915691, 화합물 → 3-O-Ethylascorbic acid
반응식
[CH2:1]([O:3][C:4]1[C@@H:9]([C@H:10]([C:12](=C(C)C)[OH:13])[OH:11])[O:8][C:6](=[O:7])[C:5]=1[OH:17])[CH3:2]>O.C(O)C>[CH2:1]([O:3][C:4]1[C@@H:9]([C@H:10]([CH2:12][OH:13])[OH:11])[O:8][C:6](=[O:7])[C:5]=1[OH:17])[CH3:2]참가 물질
4
반응 조건
- 온도
- 60 °C
실험 절차
12.4 g of the 3-O-ethyl-isopropylidene ascorbic acid prepared in Example 1 was dissolved in the mixed solvent of distilled water (10 ml)/ethanol (90 ml) together with 1.1 g of Nafion H, followed by stirring at 60° C. for 2 hours. Nafion H was eliminated by filtering and the mixture was concentrated into crude crystalline 3-ethyl-ascorbic acid. The crude crystalline 3-ethyl-ascorbic acid was re-crystallized in ethylacetate/ethanol (8:2) to give 7.6 g of white crystalline 3-O-ethyl-ascorbic acid.
후처리
- filtrationby filtering
- concentrationthe mixture was concentrated into crude crystalline 3-ethyl-ascorbic acid
- customThe crude crystalline 3-ethyl-ascorbic acid was re-crystallized in ethylacetate/ethanol (8:2)
출처 및 근거
- ORD 기록
- ord-8428ae064e2641faa58fdf215be78d89
- 출처 데이터셋
- uspto-grants-2010_11
- 특허 번호
- US07838690B2
반응 노트
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