N-[2-(2-nitrophenyl)ethyl]acetamide → HCID 19593725, 화합물

HRID 1176269노트

반응식

HRID 1176269 반응식
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[CH2:10][CH2:11][NH:12][C:13](=[O:15])[CH3:14])([O-])=O>C(O)C.[Pd]>[NH2:1][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[CH2:10][CH2:11][NH:12][C:13](=[O:15])[CH3:14]

참가 물질

4

반응물 1

HCID 2750518N-[2-(2-nitrophenyl)ethyl]acetamide

생성물 1

HCID 19593725HCID 19593725, 화합물

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

A solution of 0.95 g of N-[2-(2-nitrophenyl)ethyl]acetamide in 30 ml of ethanol is hydrogenated in the presence of 0.112 g of 10% Pd/C at room temperature over 3.5 hours. The reaction mixture is clarified by filtration and the filtrate is concentrated by evaporation. The crude title compound is obtained as a light brown solid from the residue. Rf=0.50 (9:1 dichloromethane-methanol); Rt=1.86.

후처리

  1. filtrationThe reaction mixture is clarified by filtration
  2. concentrationthe filtrate is concentrated by evaporation

출처 및 근거

ORD 기록
ord-fdbc214fcf964759b7aca0fa321b43b0
출처 데이터셋
uspto-grants-2010_11
특허 번호
US07842688B2

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