참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 2-Chloroethylbenzoate | HCID 95952 | — |
| 반응물 | 1,4,7,10,13-Pentaoxa-16-azacyclooctadecane | HCID 118578 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 2-(1,4,7,10,13-Pentaoxa-16-azacyclooctadecan-16-yl)ethyl benzoate | HCID 58974467 | 778.6% |
반응 단계
A mixture of 26.3 g of 1-aza-18-crown-6, 19.9 g of 2-chloroethyl benzoate, 21.0 g of potassium carbonate, and 60 g of N,N-dimethylformamide was stirred for 10 hours at 80° C. The reaction mixture was subjected to conventional aqueous work-up and purification by column chromatography. There was obtained 320 g of 2-(1,4,7,10,13-pentaoxa-16-azacyclo-octadecan-16-yl)ethyl benzoate (yield 75%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07276324B2 |
|---|
| 출처 데이터셋 | uspto-grants-2007_10 |
|---|
| ORD ID | ord-b4693368965a4bfe9517c4f333076d06 |
|---|
| 출처 메모 | uspto-grants-2007_10 |
|---|
