Trifluoroacetyl fluoride → 3,3-Difluoro-3-pentafluoroethoxy-2-trifluoromethylpropene

HRID 1178835

반응식

HRID 1178835 반응식
[F:1][C:2]([F:7])([F:6])[C:3]([F:5])=[O:4].[F-:8].[K+].[CH2:10]=[C:11]([C:16](OS(F)(=O)=O)([F:18])[F:17])[C:12]([F:15])([F:14])[F:13]>COCCOCCOC>[F:17][C:16]([F:18])([O:4][C:3]([F:8])([F:5])[C:2]([F:7])([F:6])[F:1])[C:11]([C:12]([F:15])([F:14])[F:13])=[CH2:10]

참가 물질

5

반응물 3

HCID 67716Trifluoroacetyl fluorideHCID 522689Potassium FluorideHCID 87741755CH2=C(CF3)CF2Oso2F

생성물 1

HCID 858876563,3-Difluoro-3-pentafluoroethoxy-2-trifluoromethylpropene수율 31%

시약·촉매·용매 1

HCID 8150Diglyme용매

반응 조건

온도
20 °C

실험 절차

Trifluoroacetyl fluoride (6 g, 0.051 mole) is bubbled into a mixture of KF (2.4 g, 0.041 mole) and dry diglyme (15 ml). The reaction mixture is stirred at 20° C. for 30 minutes and then CH2═C(CF3)CF2OSO2F (10 g, 0.041 mile) is added gradually. The resulting mixture is stirred at 20° C. for 1 hour. Hexafluoroisobutylene is distilled from the reaction mixture and the residue is poured into water. The organic layer is separated, washed in turn with aqueous sodium bicarbonate solution and water, and then dried over MgSO4. Distillation gives 3,3-Difluoro-3-pentafluoroethoxy-2-trifluoromethylpropene (CH2═C(CF3)CF2OCF2CF3) (3.5 g, 31% yield, b.pt. 67° C.).

후처리

  1. stirringThe resulting mixture is stirred at 20° C. for 1 hour
  2. distillationHexafluoroisobutylene is distilled from the reaction mixture
  3. additionthe residue is poured into water
  4. customThe organic layer is separated
  5. washwashed in turn with aqueous sodium bicarbonate solution and water
  6. dry with materialdried over MgSO4
  7. distillationDistillation

출처 및 근거

ORD 기록
ord-134a76217b16465c8f4d7d8c2b11e39d
출처 데이터셋
uspto-grants-2007_10
특허 번호
US07276624B2

연결된 노트

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