1-Isopropylpiperazine → Isopropyl-4-[3-methyl-4-(4-pyrrolidin-1-ylmethyl-piperidin-1-yl)-benzyl]-piperazine

HRID 1179397노트

반응식

[CH3:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[N:10]1[CH2:15][CH2:14][CH:13]([CH2:16][N:17]2[CH2:21][CH2:20][CH2:19][CH2:18]2)[CH2:12][CH2:11]1)[CH:5]=O.[CH:22]([N:25]1[CH2:30][CH2:29][NH:28][CH2:27][CH2:26]1)([CH3:24])[CH3:23]>>[CH:22]([N:25]1[CH2:30][CH2:29][N:28]([CH2:5][C:4]2[CH:7]=[CH:8][C:9]([N:10]3[CH2:15][CH2:14][CH:13]([CH2:16][N:17]4[CH2:21][CH2:20][CH2:19][CH2:18]4)[CH2:12][CH2:11]3)=[C:2]([CH3:1])[CH:3]=2)[CH2:27][CH2:26]1)([CH3:24])[CH3:23]

참가 물질

반응물 2

HCID 780131-Isopropylpiperazine

HCID 589780393-Methyl-4-(4-pyrrolidin-1-ylmethyl-piperidin-1-yl)-benzaldehyde

생성물 1

HCID 10363509Isopropyl-4-[3-methyl-4-(4-pyrrolidin-1-ylmethyl-piperidin-1-yl)-benzyl]-piperazine

실험 절차

Prepared from the product of Example 66 and 1-isopropylpiperazine.

출처 및 근거

ORD 기록: ord-b2f25c7e445a486a8e87e773bcbb7bef
출처 데이터셋: uspto-grants-2007_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07279491B2

반응 노트

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