4-Chloro-N-[(1H-imidazol-2-yl)methyl]aniline → HCID 10480667, 화합물

HRID 1179439노트

반응식

HRID 1179439 반응식
[CH3:1][O:2][CH:3]([O:19][CH3:20])[C@@:4]1([CH3:18])[C@@H:9]2[O:10][C@@H:8]2[C:7]2[CH:11]=[C:12]([N+:15]([O-:17])=[O:16])[CH:13]=[CH:14][C:6]=2[O:5]1.[Cl:21][C:22]1[CH:27]=[CH:26][C:25]([NH:28][CH2:29][C:30]2[NH:31][CH:32]=[CH:33][N:34]=2)=[CH:24][CH:23]=1>>[CH3:1][O:2][CH:3]([O:19][CH3:20])[C@@:4]1([CH3:18])[C@H:9]([OH:10])[C@@H:8]([N:28]([C:25]2[CH:26]=[CH:27][C:22]([Cl:21])=[CH:23][CH:24]=2)[CH2:29][C:30]2[NH:31][CH:32]=[CH:33][N:34]=2)[C:7]2[CH:11]=[C:12]([N+:15]([O-:17])=[O:16])[CH:13]=[CH:14][C:6]=2[O:5]1

참가 물질

3

반응물 2

HCID 108460134-Chloro-N-[(1H-imidazol-2-yl)methyl]anilineHCID 11065861HCID 11065861, 화합물

생성물 1

HCID 10480667HCID 10480667, 화합물수율 34%

실험 절차

The title compound (76 mg, 34%) was prepared using (2R,3R,4R)-3,4-dihydro-2-dimethoxymethyl-3,4-epoxy-2-methyl-6-nitro-2H-1-benzopyran (129 mg, 0.46 mmol) and 4-chlorophenyl-1H-imidazol-2-ylmethylamine (95 mg, 0.46 mmol), according to the same procedure used for the preparation of example 1 above.

후처리

  1. customused for the preparation of example 1 above

출처 및 근거

ORD 기록
ord-016df7201f894d5aba3eff2a04bd7c46
출처 데이터셋
uspto-grants-2007_10
특허 번호
US07279497B2

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