HCID 11065861, 화합물 → HCID 10369811, 화합물

HRID 1179449노트

반응식

HRID 1179449 반응식
[CH3:1][O:2][CH:3]([O:19][CH3:20])[C@@:4]1([CH3:18])[C@@H:9]2[O:10][C@@H:8]2[C:7]2[CH:11]=[C:12]([N+:15]([O-:17])=[O:16])[CH:13]=[CH:14][C:6]=2[O:5]1.[Br:21][C:22]1[CH:27]=[CH:26][C:25]([NH:28][CH2:29][C:30]2[NH:31][CH:32]=[CH:33][N:34]=2)=[CH:24][CH:23]=1>>[CH3:1][O:2][CH:3]([O:19][CH3:20])[C@@:4]1([CH3:18])[C@H:9]([OH:10])[C@@H:8]([N:28]([C:25]2[CH:26]=[CH:27][C:22]([Br:21])=[CH:23][CH:24]=2)[CH2:29][C:30]2[NH:31][CH:32]=[CH:33][N:34]=2)[C:7]2[CH:11]=[C:12]([N+:15]([O-:17])=[O:16])[CH:13]=[CH:14][C:6]=2[O:5]1

참가 물질

3

반응물 2

HCID 11065861HCID 11065861, 화합물HCID 61557697HCID 61557697, 화합물

생성물 1

HCID 10369811HCID 10369811, 화합물수율 60%

실험 절차

The title compound (570 mg, 60%) was prepared using (2R,3R,4R)-3,4-dihydro-2-dimethoxymethyl-3,4-epoxy-2-methyl-6-nitro-2H-1-benzopyran (500 mg, 1.78 mmol) and 4-bromophenyl-1H-imidazol-2-ylmethylamine (450 mg, 1.78 mmol), according to the same procedure used for the preparation of example 1 above.

후처리

  1. customused for the preparation of example 1 above

출처 및 근거

ORD 기록
ord-e8a122cc39274dd58a9882704cd548f1
출처 데이터셋
uspto-grants-2007_10
특허 번호
US07279497B2

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