4-Chloro-N-[(1H-imidazol-2-yl)methyl]aniline → HCID 10389911, 화합물
반응식
[C:1]([C:3]1[CH:4]=[CH:5][C:6]2[O:11][C@@:10]([CH:13]([O:16][CH3:17])[O:14][CH3:15])([CH3:12])[C@H:9]3[O:18][C@H:8]3[C:7]=2[CH:19]=1)#[N:2].[Cl:20][C:21]1[CH:26]=[CH:25][C:24]([NH:27][CH2:28][C:29]2[NH:30][CH:31]=[CH:32][N:33]=2)=[CH:23][CH:22]=1>>[C:1]([C:3]1[CH:4]=[CH:5][C:6]2[O:11][C@@:10]([CH:13]([O:16][CH3:17])[O:14][CH3:15])([CH3:12])[C@@H:9]([OH:18])[C@H:8]([N:27]([C:24]3[CH:25]=[CH:26][C:21]([Cl:20])=[CH:22][CH:23]=3)[CH2:28][C:29]3[NH:30][CH:31]=[CH:32][N:33]=3)[C:7]=2[CH:19]=1)#[N:2]참가 물질
3
실험 절차
The title compound (106 mg, 28%) was prepared using (2S,3S,4S)-6-cyano-3,4-dihydro-2-dimethoxymethyl-3,4-epoxy-2-methyl-2H-1-benzopyran (210 mg, 0.8 mmol) and 4-chlorophenyl-1H-imidazol-2-ylmethylamine (167 mg, 0.8 mmol), according to the same procedure used for the preparation of example 1 above.
후처리
- customused for the preparation of example 1 above
출처 및 근거
- ORD 기록
- ord-38442d90b04c46ee80161d9f928130e3