Carbamic chloride, N-methyl-N-phenyl- → Methyl-phenyl-carbamic Acid 4-hydroxymethyl-pyrazol-1-yl Ester

HRID 1179913

반응식

HRID 1179913 반응식
[OH:1][N:2]1[CH:6]=[C:5]([CH2:7][OH:8])[CH:4]=[N:3]1.[CH3:9][N:10]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[C:11](Cl)=[O:12]>>[OH:8][CH2:7][C:5]1[CH:4]=[N:3][N:2]([O:1][C:11](=[O:12])[N:10]([CH3:9])[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:6]=1

참가 물질

3

반응물 2

HCID 77969Carbamic chloride, N-methyl-N-phenyl-HCID 220476851-Hydroxy-4-hydroxymethylpyrazole

생성물 1

HCID 69517970Methyl-phenyl-carbamic Acid 4-hydroxymethyl-pyrazol-1-yl Ester

실험 절차

The title compound was prepared from 1-hydroxy-4-hydroxymethylpyrazole and N-methyl-N-phenylcarbamoyl chloride applying the general procedure 8. The crude product was purified by flash chromatography (Quad flash 12, EtOAc-heptane) (62%, oil).

후처리

  1. customThe crude product was purified by flash chromatography (Quad flash 12, EtOAc-heptane) (62%, oil)

출처 및 근거

ORD 기록
ord-e590bc1a1fcb455e8b7025df7a0801c1
출처 데이터셋
uspto-grants-2007_10
특허 번호
US07279470B2

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