Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trifluoroacetic acid → Trifluoroacetic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trifluoroacetic acid | HCID 6422 | — |
| 반응물 | {2-[4-(Methyl-phenyl-carbamoyloxy)-phenyl]-ethyl}-carbamic acid tertbutyl ester | HCID 69518850 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | Trifluoroacetic acid | HCID 6422 | — |
| 생성물 | Methyl-phenyl-carbamic acid 4-(2-amino-ethyl)phenyl Ester | HCID 69520583 | — |
반응 단계
{2-[4-(Methyl-phenyl-carbamoyloxy)-phenyl]-ethyl}-carbamic acid tertbutyl ester(3.7 g; 10 mmol) from above was dissolved in CH2Cl2 (90 mL). Addition of TFA (6 mL) and stirring for 4 h. The reaction mixture was evaporated to dryness and dried in vacuo at 50° C. overnight producing the title compound as a TFA salt in quantitative yield as yellow hygroscopic crystals.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07279470B2 |
| 출처 데이터셋 | uspto-grants-2007_10 |
| ORD ID | ord-72fdee7c52474c0a818034ace34960c5 |
| 출처 메모 | uspto-grants-2007_10 |