2-{1-[(Benzyloxy)methyl]cyclobutyl}ethanethioamide → {1-[(4-Methyl-1,3-thiazol-2-yl)methyl]cyclobutyl}methanol
반응식
C([O:8][CH2:9][C:10]1([CH2:14][C:15](=[S:17])[NH2:16])[CH2:13][CH2:12][CH2:11]1)C1C=CC=CC=1.Br[CH2:19][C:20](=O)[CH2:21]C(F)(F)F>>[CH3:21][C:20]1[N:16]=[C:15]([CH2:14][C:10]2([CH2:9][OH:8])[CH2:11][CH2:12][CH2:13]2)[S:17][CH:19]=1참가 물질
3
실험 절차
The title compound was prepared using the same experimental procedure as in examples 18f and 18g from 2-{1-[(benzyloxy)methyl]cyclobutyl}ethanethioamide and 1-bromo-4,4,4-trifluoro-2-butanone. 1H NMR (300 MHz, CDCl3) δ 7.25 (s, 1H), 3.35 (s, 2H), 2.82 (br s, 2H), 2.02-1.91 (m, 6H).
출처 및 근거
- ORD 기록
- ord-fadf44fe503d4920ac461fde20fa6ea6
- 출처 데이터셋
- uspto-grants-2007_10
- 특허 번호
- US07282512B2
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