tert-Butyl carbazate → Tert-butyl 2-(3-cyanobenzylidene)-1-hydrazinecarboxylate
반응식
[C:1]([C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[CH:6]=O)#[N:2].[C:11]([O:15][C:16](=[O:19])[NH:17][NH2:18])([CH3:14])([CH3:13])[CH3:12]>CCO>[C:1]([C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[CH:6]=[N:18][NH:17][C:16]([O:15][C:11]([CH3:14])([CH3:13])[CH3:12])=[O:19])#[N:2]참가 물질
4
실험 절차
3-Cyanobenzaldehyde (40.0 mmol) suspended in EtOH (100 mL) was added to a stirred solution of tert-butylcarbazate (40.0 mmol) in EtOH. The mixture was heated at reflux temperature and after 4 h the EtOH was partially evaporated in vacuo. Water (100 mL) was added and the precipitated product was collected by filtration and washed with diethylether to give tert-butyl 2-(3-cyanobenzylidene)-1-hydrazinecarboxylate as a white solid.
후처리
- temperatureThe mixture was heated
- temperatureat reflux temperature
- customafter 4 h the EtOH was partially evaporated in vacuo
- additionWater (100 mL) was added
- filtrationthe precipitated product was collected by filtration
- washwashed with diethylether
출처 및 근거
- ORD 기록
- ord-d57f2d9fe43d421ca4219b3e149b9522
- 출처 데이터셋
- uspto-grants-2007_10
- 특허 번호
- US07285547B2
반응 노트
불러오는 중…