6-Aminoquinoline → N-[3,5-bis(trifluoromethyl)phenyl]-N'-[quinolin-6-yl]urea

HRID 1181463노트

반응식

HRID 1181463 반응식
[NH2:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[CH:7][CH:6]=[CH:5]2.[F:12][C:13]([F:28])([F:27])[C:14]1[CH:15]=[C:16]([N:24]=[C:25]=[O:26])[CH:17]=[C:18]([C:20]([F:23])([F:22])[F:21])[CH:19]=1>>[F:12][C:13]([F:27])([F:28])[C:14]1[CH:15]=[C:16]([NH:24][C:25]([NH:1][C:2]2[CH:3]=[C:4]3[C:9](=[CH:10][CH:11]=2)[N:8]=[CH:7][CH:6]=[CH:5]3)=[O:26])[CH:17]=[C:18]([C:20]([F:23])([F:21])[F:22])[CH:19]=1

참가 물질

3

반응물 2

HCID 113736-AminoquinolineHCID 27333143,5-Bis(trifluoromethyl)phenyl isocyanate

생성물 1

HCID 85869770N-[3,5-bis(trifluoromethyl)phenyl]-N'-[quinolin-6-yl]urea

실험 절차

Prepared from 6-aminoquinoline and 3,5-bis(trifluoromethyl)phenyl isocyanate. m/z (ES+) 400 (M+H)+.

출처 및 근거

ORD 기록
ord-ef326adb973845d3a07fdedb8db42cfc
출처 데이터셋
uspto-grants-2007_10
특허 번호
US07285563B2

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