Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1181680생성일: 2026년 10월 27일
Triethylamine → 3-[5-methyl-2-(1-naphthylmethyl)-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]benzoic acid
https://huagongshe.com/reaction/1181680
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | 3-Carboxybenzaldehyde | HCID 12077 | — |
| 반응물 | 1-Naphthaldehyde (1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)hydrazone | HCID 69845528 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 3-[5-methyl-2-(1-naphthylmethyl)-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]benzoic acid | HCID 136334115 | — |
반응 단계
1-naphthaldehyde (1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)hydrazone (2.12 g) and triethylamine (0.8 ml) was added to a suspension of Resin bound 3-formylbenzoic acid in dimethylformamide (15 ml), and the mixture was shaken at 90° C. for 16 hours. The resin was filtered and washed (3 times) DMF, CH2Cl2, MeOH, CH2Cl2, and dried in vacuum to give the subtitle compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US07285558B2 |
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| 출처 데이터셋 | uspto-grants-2007_10 |
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| ORD ID | ord-d0dd19257cd84a4faa51d8b762041751 |
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| 출처 메모 | uspto-grants-2007_10 |
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