Diethyl cyanophosphonate → 5-{2-[(5-chloro-1H-indol-3-yl)methyl]-7-isobutyl-5-methyl-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl}-1-methyl-N-(pyridin-4-ylmethyl)-1H-pyrrole-3-carboxamide

참여 물질

역할	이름	HCID	투입량
반응물	Diethyl cyanophosphonate	HCID 76257	—
반응물	4-(Methylamino)pyridine	HCID 123098	—
반응물	5-{2-[(5-chloro-1H-indol-3-yl)methyl]-7-isobutyl-5-methyl-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl}-1-methyl-1H-pyrrole-3-carboxylic acid	HCID 58981063	—
생성물	5-{2-[(5-chloro-1H-indol-3-yl)methyl]-7-isobutyl-5-methyl-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl}-1-methyl-N-(pyridin-4-ylmethyl)-1H-pyrrole-3-carboxamide	HCID 58981047	—

반응 단계

This compound was synthesized by the reaction of 5-{2-[(5-chloro-1H-indol-3-yl)methyl]-7-isobutyl-5-methyl-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl}-1-methyl-1H-pyrrole-3-carboxylic acid and pyridin-4-yl-methylamine using diethyl cyanophosphonate as a coupling reagent. Mass: 599.15 (M+H).

출처 및 근거

DOI	10.6084/m9.figshare.5104873.v1
특허 번호	US07285558B2
출처 데이터셋	uspto-grants-2007_10
ORD ID	ord-15a29db017b643588d370abb3997a45c
출처 메모	uspto-grants-2007_10