1-Methyl-2-imidazolecarboxaldehyde → 7-isobutyl-5-methyl-3-(1-methyl-1H-imidazol-2-yl)-2-[(5-nitro-1H-indol-3-yl)methyl]-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

HRID 1181749

반응식

HRID 1181749 반응식
[NH:1]([C:3]1[N:8]([CH2:9][CH:10]([CH3:12])[CH3:11])[C:7](=[O:13])[N:6]([CH3:14])[C:5](=[O:15])[CH:4]=1)[NH2:2].[N+:16]([C:19]1[CH:20]=[C:21]2[C:25](=[CH:26][CH:27]=1)[NH:24][CH:23]=[C:22]2[CH:28]=O)([O-:18])=[O:17].[CH3:30][N:31]1[CH:35]=[CH:34][N:33]=[C:32]1[CH:36]=O>>[CH2:9]([N:8]1[C:3]2=[N:1][N:2]([CH2:28][C:22]3[C:21]4[C:25](=[CH:26][CH:27]=[C:19]([N+:16]([O-:18])=[O:17])[CH:20]=4)[NH:24][CH:23]=3)[C:36]([C:32]3[N:31]([CH3:30])[CH:35]=[CH:34][N:33]=3)=[C:4]2[C:5](=[O:15])[N:6]([CH3:14])[C:7]1=[O:13])[CH:10]([CH3:11])[CH3:12]

참가 물질

4

반응물 3

HCID 1395751-Methyl-2-imidazolecarboxaldehydeHCID 2460395-nitro-1H-indole-3-carbaldehydeHCID 193560846-hydrazino-1-isobutyl-3-methyl-2,4(1H,3H)-pyrimidinedione

생성물 1

HCID 589811457-isobutyl-5-methyl-3-(1-methyl-1H-imidazol-2-yl)-2-[(5-nitro-1H-indol-3-yl)methyl]-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

실험 절차

This compound was made following the procedure described above, starting with 6-hydrazino-1-isobutyl-3-methylpyrimidine-2,4(1H,3H)-dione, and condensing first with 5-nitro-1H-indole-3-carbaldehyde, followed by 1-methyl-1H-imidazole-2-carbaldehyde. Mass: 477.19 (M+H).

출처 및 근거

ORD 기록
ord-13e52587452f4ec28581a223e2049c83
출처 데이터셋
uspto-grants-2007_10
특허 번호
US07285558B2

연결된 노트

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