1-Ethyl-2-pyrrolecarboxaldehyde → 2-[(5-chloro-1H-indol-3-yl)methyl]-3-(1-ethyl-1H-pyrrol-2-yl)-7-isobutyl-5-methyl-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

HRID 1181832

반응식

HRID 1181832 반응식
[NH:1]([C:3]1[N:8]([CH2:9][CH:10]([CH3:12])[CH3:11])[C:7](=[O:13])[N:6]([CH3:14])[C:5](=[O:15])[CH:4]=1)[NH2:2].[Cl:16][C:17]1[CH:18]=[C:19]2[C:23](=[CH:24][CH:25]=1)[NH:22][CH:21]=[C:20]2[CH:26]=O.[CH2:28]([N:30]1[CH:34]=[CH:33][CH:32]=[C:31]1[CH:35]=O)[CH3:29]>>[Cl:16][C:17]1[CH:18]=[C:19]2[C:23](=[CH:24][CH:25]=1)[NH:22][CH:21]=[C:20]2[CH2:26][N:2]1[C:35]([C:31]2[N:30]([CH2:28][CH3:29])[CH:34]=[CH:33][CH:32]=2)=[C:4]2[C:3]([N:8]([CH2:9][CH:10]([CH3:11])[CH3:12])[C:7](=[O:13])[N:6]([CH3:14])[C:5]2=[O:15])=[N:1]1

참가 물질

4

반응물 3

HCID 5793381-Ethyl-2-pyrrolecarboxaldehydeHCID 27953745-chloro-1H-indole-3-carbaldehydeHCID 193560846-hydrazino-1-isobutyl-3-methyl-2,4(1H,3H)-pyrimidinedione

생성물 1

HCID 589810352-[(5-chloro-1H-indol-3-yl)methyl]-3-(1-ethyl-1H-pyrrol-2-yl)-7-isobutyl-5-methyl-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

실험 절차

This compound was made following the procedure described above, starting with 6-hydrazino-1-isobutyl-3-methylpyrimidine-2,4(1H,3H)-dione and condensing first with 5-chloro-1H-indole-3-carbaldehyde, followed by 1-ethyl-1H-pyrrole-2-carbaldehyde. 479 (M+H).

출처 및 근거

ORD 기록
ord-cc2efaa07f084ae29a3511a50584f671
출처 데이터셋
uspto-grants-2007_10
특허 번호
US07285558B2

연결된 노트

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