Adipic Dihydrazide → HCID 178461152, 화합물

HRID 1183229

반응식

HRID 1183229 반응식
[CH3:1][C@@H:2]1[C@@H:16]2[C:11](=[C:12]([OH:31])[C@:13]3([OH:30])[C:21](=[O:22])[C:20]([C:23]([NH2:25])=[O:24])=[C:19]([OH:26])[C@@H:18]([N:27]([CH3:29])[CH3:28])[C@@H:14]3[C@H:15]2[OH:17])[C:9](=[O:10])[C:8]2[C:7]([OH:32])=[CH:6][CH:5]=[CH:4][C:3]1=2.Cl.C(NN)(=O)CCCCC(NN)=O>>[CH3:1][C@@H:2]1[C@@H:16]2[C:11](=[C:12]([OH:31])[C@:13]3([OH:30])[C:21](=[O:22])[C:20]([C:23]([NH2:25])=[O:24])=[C:19]([OH:26])[C@@H:18]([N:27]([CH3:28])[CH3:29])[C@@H:14]3[C@H:15]2[OH:17])[C:9](=[O:10])[C:8]2[C:7]([OH:32])=[CH:6][CH:5]=[CH:4][C:3]1=2

참가 물질

3

반응물 2

HCID 66117Adipic DihydrazideHCID 178461154HCID 178461154, 화합물

생성물 1

HCID 178461152HCID 178461152, 화합물

실험 절차

Doxycycline-HCl (100 mg) was finely ground with 90 mg DSS (Mw, 500,000) and 8 mg adipic dihydrazide. The mixture was loaded into a 3-ml syringe fitted with a to Luer plug. Oxidized dextran solution (1 ml, Mw of 500,000; 66 mg/ml) was loaded into a second syringe. An injectable formulation was formed after connecting the syringes and performing 30 reciprocations of the syringe plungers.

후처리

  1. customThe mixture was loaded into a 3-ml syringe
  2. customfitted with a to Luer plug
  3. customwas loaded into a second syringe
  4. customAn injectable formulation was formed

출처 및 근거

ORD 기록
ord-576157b10cfc483e922cb3b760bb55ed
출처 데이터셋
uspto-grants-2014_03
특허 번호
US08664280B2

연결된 노트

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