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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1183472생성일: 2026년 10월 27일

2-Bromo-6-(1H-pyrazol-1-yl)pyridine → 1-{4'-[3-Methyl-4-(6-pyrazol-1-yl-pyridin-2-ylamino)-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl ester

https://huagongshe.com/reaction/1183472

반응식

참여 물질

역할이름HCID투입량
반응물2-Bromo-6-(1H-pyrazol-1-yl)pyridineHCID 7060529—
반응물1-[4'-(4-Amino-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl esterHCID 66577195—
생성물1-{4'-[3-Methyl-4-(6-pyrazol-1-yl-pyridin-2-ylamino)-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl esterHCID 66579705—

반응 단계

Prepared according to the procedure described in Example 68, Step 2, using 1-[4′-(4-amino-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-cyclopropanecarboxylic acid ethyl ester and 2-bromo-6-pyrazol-1-yl-pyridine.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08664220B2
출처 데이터셋uspto-grants-2014_03
ORD IDord-d5562e619d904607a801d8a0ff2c0f7a
출처 메모uspto-grants-2014_03