2-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamide → Methyl 1-{[6-({3-(aminocarbonyl)-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-thienyl}amino)pyridin-2-yl]methyl}-1H-1,2,3-triazole-5-carboxylate

HRID 118359

반응식

HRID 118359 반응식
[Br:1][c:2]1[cH:3][cH:4][cH:5][c:6]([CH2:8][n:9]2[n:10][n:11][cH:12][c:13]2[C:14](=[O:15])[O:16][CH3:17])[n:7]1.[NH2:18][c:19]1[s:20][c:21](-[c:27]2[c:28]([F:38])[cH:29][c:30]([C:34]([CH3:35])([CH3:36])[OH:37])[cH:31][c:32]2[F:33])[cH:22][c:23]1[C:24](=[O:25])[NH2:26]>>[c:2]1([NH:18][c:19]2[s:20][c:21](-[c:27]3[c:28]([F:38])[cH:29][c:30]([C:34]([CH3:35])([CH3:36])[OH:37])[cH:31][c:32]3[F:33])[cH:22][c:23]2[C:24](=[O:25])[NH2:26])[cH:3][cH:4][cH:5][c:6]([CH2:8][n:9]2[n:10][n:11][cH:12][c:13]2[C:14](=[O:15])[O:16][CH3:17])[n:7]1

참가 물질

3

반응물 2

HCID 595256192-Amino-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]thiophene-3-carboxamideHCID 59525904Methyl 1-[(6-bromopyridin-2-yl)methyl]-1H-1,2,3-triazole-5-carboxylate

생성물 1

HCID 59526199Methyl 1-{[6-({3-(aminocarbonyl)-5-[2,6-difluoro-4-(1-hydroxy-1-methylethyl)phenyl]-2-thienyl}amino)pyridin-2-yl]methyl}-1H-1,2,3-triazole-5-carboxylate

출처 및 근거

ORD 기록
ord-c7c63e56ba164836a022fba6c11343b7
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

연결된 노트

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