4-Hydroxyphenylpyruvic Acid → 8-cyclopropyl-2-[(4-hydroxyphenyl)methyl]-6-phenyl-7H-imidazo[1,2-a]pyrazin-3-one

HRID 1184328

반응식

HRID 1184328 반응식
[CH:1]1([C:4]2[C:5]([NH2:16])=[N:6][CH:7]=[C:8]([C:10]3[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=3)[N:9]=2)[CH2:3][CH2:2]1.[OH:17][C:18]1[CH:23]=[CH:22][C:21]([CH2:24][C:25](=O)[C:26](O)=[O:27])=[CH:20][CH:19]=1>>[CH:1]1([C:4]2[NH:9][C:8]([C:10]3[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=3)=[CH:7][N:6]3[C:26](=[O:27])[C:25]([CH2:24][C:21]4[CH:22]=[CH:23][C:18]([OH:17])=[CH:19][CH:20]=4)=[N:16][C:5]=23)[CH2:3][CH2:2]1

참가 물질

3

반응물 2

HCID 9794-Hydroxyphenylpyruvic AcidHCID 674943853-Cyclopropyl-5-phenylpyrazin-2-amine

생성물 1

HCID 1785156458-cyclopropyl-2-[(4-hydroxyphenyl)methyl]-6-phenyl-7H-imidazo[1,2-a]pyrazin-3-one

실험 절차

Synthesized using method A with 3-cyclopropyl-5-phenylpyrazin-2-amine and 3-(4-hydroxyphenyl)-2-oxopropanoic acid as starting materials. Exact mass calculated for C22H18N3O2+ m/z−356.14, found m/z−356.

후처리

  1. customSynthesized

출처 및 근거

ORD 기록
ord-18155ac5c9cd4315bf651cc5302ea9d9
출처 데이터셋
uspto-grants-2014_03
특허 번호
US08669103B2

연결된 노트

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