Dihydro-8-methyl-2H-1,4-benzoxazine-2-carboxamide → Dihydro-8-methyl-2H-1,4-benzoxazine-2-methanamine

반응식

FC1C2OC(CN)CNC=2C=CC=1.[CH3:14][C:15]1[C:24]2[O:23][CH:22]([C:25]([NH2:27])=O)[CH2:21][NH:20][C:19]=2[CH:18]=[CH:17][CH:16]=1>>[CH3:14][C:15]1[C:24]2[O:23][CH:22]([CH2:25][NH2:27])[CH2:21][NH:20][C:19]=2[CH:18]=[CH:17][CH:16]=1

참가 물질

반응물 2

HCID 67497427Dihydro-8-methyl-2H-1,4-benzoxazine-2-carboxamide

HCID 67497870Dihydro-8-fluoro-2H-1,4-benzoxazine-2-methanamine

생성물 1

HCID 67498071Dihydro-8-methyl-2H-1,4-benzoxazine-2-methanamine

실험 절차

This compound is obtained using the same experimental conditions as those used for the synthesis of intermediate 2b but by replacing 3,4-dihydro-8-fluoro-2H-1,4-benzoxazine-2-carboxamide (4b) with 3,4-dihydro-8-methyl-2H-1,4-benzoxazine-2-carboxamide (4c). The title compound of formula (2c) is obtained.

후처리

customThis compound is obtained

출처 및 근거

ORD 기록: ord-bb69e053b920402581cdc48e7e79ae79
출처 데이터셋: uspto-grants-2014_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08669250B2

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