Glufosinate → HCID 178476818, 화합물

HRID 1184981

반응식

HRID 1184981 반응식
C[P:2]([OH:11])([CH2:4][CH2:5][CH:6](N)C(O)=O)=[O:3].P(Cl)(Cl)Cl.[Cl-:16].[Cl-].[Cl-].[Cl-].[Al+3].[CH2:21]=[CH2:22]>C(O)C>[Cl:16][CH2:6][CH2:5][CH2:4][PH:2](=[O:3])[O:11][CH2:21][CH3:22]

참가 물질

6

반응물 4

HCID 4794GlufosinateHCID 6325EthyleneHCID 24387Phosphorus trichlorideHCID 25114082Aluminum tetrachloride

생성물 1

HCID 178476818HCID 178476818, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

Alternatively, another method of producing glufosinate generally comprises converting phosphorus trichloride to an adduct of methylphosphonous trichloride and aluminum tetrachloride (i.e., CH3PCl3.AlCl4). The adduct may be reacted with ethylene to form an intermediate adduct, which then may be reacted with ethanol to form ethyl 1-(2-chloroethyl)-methylphosphinate. Ethyl 1-(2-chlorethyl)-methylphosphinate may then be reacted with potassium hydroxide and ethanol to prepare the requisite ethyl vinylphosphinate precursor. The ethyl vinylphosphinate precursor is subjected to hydroformylation-aminocarbonylation, followed by hydrolysis of the hydroformylation-aminocarbonylation product in the presence of hydrochloric acid to produce glufosinate.

후처리

  1. customto form an intermediate adduct, which

출처 및 근거

ORD 기록
ord-b7d56bc03a6b4088809a1fff735d8036
출처 데이터셋
uspto-grants-2014_03
특허 번호
US08669396B2

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