Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → N-(3-chloroquinoxalin-2-yl)-2-fluorobenzenesulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 2,3-Dichloroquinoxaline | HCID 16659 | — |
| 반응물 | 2-Fluorobenzenesulfonamide | HCID 193663 | — |
| 용매 | Dimethyl Sulfoxide | HCID 679 | — |
| 생성물 | N-(3-chloroquinoxalin-2-yl)-2-fluorobenzenesulfonamide | HCID 86657929 | 75% |
반응 단계
According to Reference Example 6-1, by use of 2,3-dichloroquinoxaline (80 mg, 0.40 mmol), dimethyl sulfoxide (2 mL), 2-fluorobenzenesulfonamide (70 mg, 0.40 mmol) and potassium carbonate (56 mg, 0.40 mmol), the mixture was stirred and reacted at 150° C. for 1.5 hours. Thus, N-(3-chloroquinoxalin-2-yl)-2-fluorobenzenesulfonamide (Compound AE) (101 mg, yield: 75%) was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08673908B2 |
| 출처 데이터셋 | uspto-grants-2014_03 |
| ORD ID | ord-13da6086a4ae41d0b7a6d7e9b4af0ba8 |
| 출처 메모 | uspto-grants-2014_03 |