Methylamine → Imidazo(1,2-a)pyrazin-8-amine, 3-bromo-N-methyl-

HRID 1186463노트

반응식

HRID 1186463 반응식
[Br:1][C:2]1[N:6]2[CH:7]=[CH:8][N:9]=[C:10](Cl)[C:5]2=[N:4][CH:3]=1.[CH3:12][NH2:13]>CCO>[Br:1][C:2]1[N:6]2[CH:7]=[CH:8][N:9]=[C:10]([NH:13][CH3:12])[C:5]2=[N:4][CH:3]=1

참가 물질

4

반응물 2

HCID 6329MethylamineHCID 100598493-Bromo-8-chloroimidazo[1,2-a]pyrazine

생성물 1

HCID 3088360Imidazo(1,2-a)pyrazin-8-amine, 3-bromo-N-methyl-

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

(3-Bromo-imidazo[1,2-a]pyrazin-8-yl)-methyl-amine was prepared by a process analogous to that described in Example 2 starting from 3-bromo-8-chloro-imidazo[1,2-a]pyrazine and excess methylamine (33% weight in EtOH) at room temperature in EtOH.

출처 및 근거

ORD 기록
ord-27585390005d406b9c863723c9d1e49b
출처 데이터셋
uspto-grants-2014_03
특허 번호
US08673905B2

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