돌아가기
Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1186470생성일: 2026년 10월 27일

Isopropylamine → [3-(2-Isopropylamino-pyrimidin-4-yl)-imidazo[1,2-a]pyrazin-8-yl]-(2-methanesulfonyl-ethyl)-amine

https://huagongshe.com/reaction/1186470

반응식

참여 물질

역할이름HCID투입량
반응물IsopropylamineHCID 6363—
반응물2-(Methylthio)-4-(tributylstannyl)pyrimidineHCID 2763261—
반응물(3-Bromo-imidazo[1,2-a]pyrazin-8-yl)-(2-methanesulfonyl-ethyl)-carbamic acid tert-butyl esterHCID 68226902—
생성물[3-(2-Isopropylamino-pyrimidin-4-yl)-imidazo[1,2-a]pyrazin-8-yl]-(2-methanesulfonyl-ethyl)-amineHCID 66548084—

반응 단계

[3-(2-Isopropylamino-pyrimidin-4-yl)-imidazo[1,2-a]pyrazin-8-yl]-(2-methanesulfonyl-ethyl)-amine was prepared by a process analogous to that described in Example 12 starting from (3-bromo-imidazo[1,2-a]pyrazin-8-yl)-(2-methanesulfonyl-ethyl)-carbamic acid tert-butyl ester (from Example 5 supra), 2-methylsulfanyl-4-tributylstannanyl-pyrimidine, and isopropylamine. LC-MS: [M+H]+ 376.3.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08673905B2
출처 데이터셋uspto-grants-2014_03
ORD IDord-40c6487770b34ddc8fc8aad6e669d823
출처 메모uspto-grants-2014_03