Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Morpholine → 2-[3-(2-Morpholin-4-yl-pyrimidin-4-yl)-imidazo[1,2-a]pyrazin-8-ylamino]-ethanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Morpholine | HCID 8083 | — |
| 반응물 | 2-(Methylthio)-4-(tributylstannyl)pyrimidine | HCID 2763261 | — |
| 반응물 | 2-[(3-Bromoimidazo[1,2-a]pyrazin-8-yl)amino]ethan-1-ol | HCID 21070904 | — |
| 생성물 | 2-[3-(2-Morpholin-4-yl-pyrimidin-4-yl)-imidazo[1,2-a]pyrazin-8-ylamino]-ethanol | HCID 66548436 | — |
반응 단계
2-[3-(2-Morpholin-4-yl-pyrimidin-4-yl)-imidazo[1,2-a]pyrazin-8-ylamino]-ethanol was prepared by a process analogous to that described in Example 12 starting from 2-(3-bromo-imidazo[1,2-a]pyrazin-8-ylamino)-ethanol (from Example 2 supra), 2-methylsulfanyl-4-tributylstannanyl-pyrimidine, and morpholine. LC-MS: [M+H]+ 342.3.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08673905B2 |
| 출처 데이터셋 | uspto-grants-2014_03 |
| ORD ID | ord-9e597f9266274faeb2627acc67df9a65 |
| 출처 메모 | uspto-grants-2014_03 |