Methylamine → HCID 66548439, 화합물

HRID 1186485

반응식

HRID 1186485 반응식
Br[C:2]1[N:6]2[CH:7]=[CH:8][N:9]=[C:10]([NH:11][CH2:12][CH2:13][OH:14])[C:5]2=[N:4][CH:3]=1.CS[C:17]1[N:22]=[C:21]([Sn](CCCC)(CCCC)CCCC)[CH:20]=[CH:19][N:18]=1.[CH3:36][NH2:37]>>[CH3:36][NH:37][C:17]1[N:22]=[C:21]([C:2]2[N:6]3[CH:7]=[CH:8][N:9]=[C:10]([NH:11][CH2:12][CH2:13][OH:14])[C:5]3=[N:4][CH:3]=2)[CH:20]=[CH:19][N:18]=1

참가 물질

4

반응물 3

HCID 6329MethylamineHCID 27632612-(Methylthio)-4-(tributylstannyl)pyrimidineHCID 210709042-[(3-Bromoimidazo[1,2-a]pyrazin-8-yl)amino]ethan-1-ol

생성물 1

HCID 66548439HCID 66548439, 화합물

실험 절차

2-[3-(2-Methylamino-pyrimidin-4-yl)-imidazo[1,2-a]pyrazin-8-ylamino]-ethanol was prepared by a process analogous to that described in Example 12 starting from 2-(3-bromo-imidazo[1,2-a]pyrazin-8-ylamino)-ethanol (from Example 2 supra), 2-methylsulfanyl-4-tributylstannanyl-pyrimidine, and methylamine. LC-MS: [M+H]+ 286.2.

출처 및 근거

ORD 기록
ord-9a53e6341d92478dbbcb909c61d09903
출처 데이터셋
uspto-grants-2014_03
특허 번호
US08673905B2

연결된 노트

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